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c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells †

Angiogenic vasa vasorum (VV) expansion plays an essential role in the pathogenesis of hypoxia-induced pulmonary hypertension (PH), a cardiovascular disease. We previously showed that extracellular ATP released under hypoxic conditions is an autocrine/paracrine, the angiogenic factor for pulmonary ar...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Strassheim, Derek, Karoor, Vijaya, Nijmeh, Hala, Weston, Philip, Lapel, Martin, Schaack, Jerome, Sullivan, Timothy, Dempsey, Edward C., Stenmark, Kurt R., Gerasimovskaya, Evgenia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072142/
https://ncbi.nlm.nih.gov/pubmed/32054096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020416
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