EMERGENCE OF FIBROBLASTS WITH A PROINFLAMMATORY EPIGENETICALLY ALTERED PHENOTYPE IN SEVERE HYPOXIC PULMONARY HYPERTENSION

Persistent accumulation of monocytes/macrophages in the pulmonary artery adventitial/perivascular areas of animals and humans with pulmonary hypertension has been documented. The cellular mechanisms contributing to chronic inflammatory responses remain unclear. We hypothesized that perivascular infl...

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Autores principales: Li, Min, Riddle, Suzette R., Frid, Maria G., El Kasmi, Karim C., McKinsey, Timothy A., Sokol, Ronald J., Strassheim, Derek, Meyrick, Barbara, Yeager, Michael E., Flockton, Amanda R., McKeon, B. Alexandre, Lemon, Douglas D., Horn, Todd R., Anwar, Adil, Barajas, Carlos, Stenmark, Kurt R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159707/
https://ncbi.nlm.nih.gov/pubmed/21813768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100479
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