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Development of a Novel Nonradiometric Assay for Nucleic Acid Binding to TDP-43 Suitable for High-Throughput Screening Using AlphaScreen(®) Technology

TAR DNA binding protein 43 (TDP-43) is a nucleic acid binding protein that is associated with the pathology of cystic fibrosis and neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal lobar dementia. We have developed a robust, quantitative, nonradiometric high-through...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: CASSEL, JOEL A., BLASS, BENJAMIN E., REITZ, ALLEN B., PAWLYK, AARON C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426361/
https://ncbi.nlm.nih.gov/pubmed/20855563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057110382778
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