HLA Class I Antigen Processing Machinery Component Expression and Intratumoral T-Cell Infiltrate as Independent Prognostic Markers in Ovarian Carcinoma

PURPOSE: Defects in the antigen processing machinery (APM) may provide tumor cells with a mechanism to escape immune recognition. The purpose of this study is to determine the clinical significance of APM component down-regulation and tumor-infiltrating T cells in ovarian carcinoma. EXPERIMENTAL DES...

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Autores principales: Han, Liz Y., Fletcher, Mavis S., Urbauer, Diana L., Mueller, Peter, Landen, Charles N., Kamat, Aparna A., Lin, Yvonne G., Merritt, William M., Spannuth, Whitney A., Deavers, Michael T., De Geest, Koen, Gershenson, David M., Lutgendorf, Susan K., Ferrone, Soldano, Sood, Anil K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426216/
https://ncbi.nlm.nih.gov/pubmed/18519766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4433
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