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Intrastriatal transplantation of neurotrophic factor-secreting human mesenchymal stem cells improves motor function and extends survival in R6/2 transgenic mouse model for Huntington's disease

Stem cell-based treatment for Huntington's disease (HD) is an expanding field of research. Although various stem cells have been shown to be beneficial in vivo, no long standing clinical effect has been demonstrated. To address this issue, we are developing a stem cell-based therapy designed to...

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Detalhes bibliográficos
Main Authors: Sadan, Ofer, Melamed, Eldad, Offen, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426086/
https://ncbi.nlm.nih.gov/pubmed/22953237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/4f7f6dc013d4e
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