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Intrastriatal transplantation of neurotrophic factor-secreting human mesenchymal stem cells improves motor function and extends survival in R6/2 transgenic mouse model for Huntington's disease

Stem cell-based treatment for Huntington's disease (HD) is an expanding field of research. Although various stem cells have been shown to be beneficial in vivo, no long standing clinical effect has been demonstrated. To address this issue, we are developing a stem cell-based therapy designed to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sadan, Ofer, Melamed, Eldad, Offen, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426086/
https://ncbi.nlm.nih.gov/pubmed/22953237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/4f7f6dc013d4e
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