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Crystal Structure of Firefly Luciferase in a Second Catalytic Conformation Supports a Domain Alternation Mechanism

Beetle luciferases catalyze a two-step reaction that includes the initial adenylation of the luciferin substrate, followed by an oxidative decarboxylation that ultimately produces light. Evidence for homologous acyl-CoA synthetases supports a domain alternation catalytic mechanism in which these enz...

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Hlavní autoři: Sundlov, Jesse A., Fontaine, Danielle M., Southworth, Tara L., Branchini, Bruce R., Gulick, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425952/
https://ncbi.nlm.nih.gov/pubmed/22852753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300934s
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