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Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production
Insulin-like growth factors (IGFs) are critical for development and growth of skeletal muscles, but because several tissues produce IGFs, it is not clear which source is necessary or sufficient for muscle growth. Because it is critical for production of both IGF-I and IGF-II, we ablated glucose-regu...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Federation of American Societies for Experimental Biology
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425820/ https://ncbi.nlm.nih.gov/pubmed/22649033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-203026 |
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