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An essential role for ATP binding and hydrolysis in the chaperone activity of GRP94 in cells
Glucose-regulated protein 94 (GRP94) is an endoplasmic reticulum (ER) chaperone for which only few client proteins and no cofactors are known and whose mode of action is unclear. To decipher the mode of GRP94 action in vivo, we exploited our finding that GRP94 is necessary for the production of insu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710619/ https://ncbi.nlm.nih.gov/pubmed/19553200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902626106 |
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