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Impaired propulsive motility in the distal but not proximal colon of BK channel β1-subunit knockout mice
BACKGROUND: Large conductance Ca(2+)-activated K(+) (BK) channels regulate smooth muscle tone. The BK channel β1-subunit increases Ca(2+) sensitivity of the α-subunit in smooth muscle. We studied β1-subunit knockout (KO) mice to determine if gastrointestinal (GI) motility was altered. METHODS: Colon...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425659/ https://ncbi.nlm.nih.gov/pubmed/22830588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2012.01981.x |
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