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Engineering of an Artificial Light-Modulated Potassium Channel

Ion Channel-Coupled Receptors (ICCRs) are artificial receptor-channel fusion proteins designed to couple ligand binding to channel gating. We previously validated the ICCR concept with various G protein-coupled receptors (GPCRs) fused with the inward rectifying potassium channel Kir6.2. Here we char...

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Autors principals: Caro, Lydia N., Moreau, Christophe J., Estrada-Mondragón, Argel, Ernst, Oliver P., Vivaudou, Michel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425490/
https://ncbi.nlm.nih.gov/pubmed/22928030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043766
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