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Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins
Ultralow molecular weight (ULMW) heparins are sulfated glycans that are clinically used to treat thrombotic disorders. ULMW heparins range from 1500 to 3000 daltons, corresponding from 5 to 10 saccharide units. The commercial drug Arixtra (fondaparinux sodium) is a structurally homogeneous ULMW hepa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425363/ https://ncbi.nlm.nih.gov/pubmed/22034431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1207478 |
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