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Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16S ribosomal RNA of Escherichia coli: preparation of m-6-2-A-C-C-U-C-C and A-C-C-U-C-m-4-2C via phosphotriester intermediates.

The synthesis of two fully-protected hexanucleotides (11a and 11b) via a phosphotriester approach, which is based on the use of two types of protecting groups for the internucleotide linkages, i.e. one 2,2,2-tribromo-ethyl at the 5'-terminus and four 2-chlorophenyl groups for the remaining link...

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Bibliografiske detaljer
Main Authors: van Boom, J H, Burgers, P M, van der Marel, G, Wille, G
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC342477/
https://ncbi.nlm.nih.gov/pubmed/325521
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