Inhibition of Indoleamine-2,3-dioxygenase (IDO) in Glioblastoma Cells by Oncolytic Herpes Simplex Virus

Successful oncolytic virus treatment of malignant glioblastoma multiforme depends on widespread tumor-specific lytic virus replication and escape from mitigating innate immune responses to infection. Here we characterize a new HSV vector, JD0G, that is deleted for ICP0 and the joint sequences separa...

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Main Authors: Reinhart, Bonnie, Mazzacurati, Lucia, Forero, Adriana, Hong, Chang-Sook, Eguchi, Junichi, Okada, Hideho, Fellows, Wendy, Niranjan, Ajay, Cohen, Justus B., Glorioso, Joseph C., Grandi, Paola
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424635/
https://ncbi.nlm.nih.gov/pubmed/22924042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/815465
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