The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ

Although most DNA polymerases discriminate against ribonucleotide triphosphaets (rNTPs) during DNA synthesis, recent studies have shown that large numbers of ribonucleotides are incorporated into the eukaryotic nuclear genome. Here, we investigate how a DNA polymerase can stably incorporate an rNTP....

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Bibliographische Detailangaben
Hauptverfasser: Gosavi, Rajendrakumar A., Moon, Andrea F., Kunkel, Thomas A., Pedersen, Lars C., Bebenek, Katarzyna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424563/
https://ncbi.nlm.nih.gov/pubmed/22584622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks413
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