Elaidyl-sulfamide, an oleoylethanolamide-modelled PPARα agonist, reduces body weight gain and plasma cholesterol in rats

We have modelled elaidyl-sulfamide (ES), a sulfamoyl analogue of oleoylethanolamide (OEA). ES is a lipid mediator of satiety that works through the peroxisome proliferator-activated receptor alpha (PPARα). We have characterised the pharmacological profile of ES (0.3–3 mg/kg body weight) by means of...

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Hlavní autoři: Decara, Juan Manuel, Romero-Cuevas, Miguel, Rivera, Patricia, Macias-González, Manuel, Vida, Margarita, Pavón, Francisco J., Serrano, Antonia, Cano, Carolina, Fresno, Nieves, Pérez-Fernández, Ruth, Rodríguez de Fonseca, Fernando, Suárez, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Limited 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424463/
https://ncbi.nlm.nih.gov/pubmed/22736460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009233
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