Computational and Biological Evaluation of N-octadecyl-N′-propylsulfamide, a Selective PPARα Agonist Structurally Related to N-acylethanolamines

To further understand the pharmacological properties of N-oleoylethanolamine (OEA), a naturally occurring lipid that activates peroxisome proliferator-activated receptor alpha (PPARα), we designed sulfamoyl analogs based on its structure. Among the compounds tested, N-octadecyl-N′-propylsulfamide (C...

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Detalhes bibliográficos
Main Authors: Moreno-Santos, Inmaculada, Pavón, Francisco Javier, Romero-Cuevas, Miguel, Serrano, Antonia, Cano, Carolina, Suardíaz, Margarita, Decara, Juan, Suarez, Juan, de Fonseca, Fernando Rodríguez, Macías-González, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961330/
https://ncbi.nlm.nih.gov/pubmed/24651609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092195
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