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Discovery of Potent Dual PPARα Agonists/CB1 Ligands
[Image: see text] This letter describes the synthesis and in vitro and in vivo evaluation of dual ligands targeting the cannabinoid and peroxisome proliferator-activated receptors (PPAR). These compounds were obtained from fusing the pharmacophores of fibrates and the diarylpyrazole rimonabant, a ca...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical Society
2011
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056814/ https://ncbi.nlm.nih.gov/pubmed/24936232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200091q |
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