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Evolutionary Meta-Analysis of Association Studies Reveals Ancient Constraints Affecting Disease Marker Discovery

Genome-wide disease association studies contrast genetic variation between disease cohorts and healthy populations to discover single nucleotide polymorphisms (SNPs) and other genetic markers revealing underlying genetic architectures of human diseases. Despite scores of efforts over the past decade...

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書誌詳細
主要な著者: Dudley, Joel T., Chen, Rong, Sanderford, Maxwell, Butte, Atul J., Kumar, Sudhir
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424407/
https://ncbi.nlm.nih.gov/pubmed/22389448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss079
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