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Human genomic disease variants: A neutral evolutionary explanation

Many perspectives on the role of evolution in human health include nonempirical assumptions concerning the adaptive evolutionary origins of human diseases. Evolutionary analyses of the increasing wealth of clinical and population genomic data have begun to challenge these presumptions. In order to s...

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Detalhes bibliográficos
Main Authors: Dudley, Joel T., Kim, Yuseob, Liu, Li, Markov, Glenn J., Gerold, Kristyn, Chen, Rong, Butte, Atul J., Kumar, Sudhir
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409252/
https://ncbi.nlm.nih.gov/pubmed/22665443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133702.111
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