Evolutionary Meta-Analysis of Association Studies Reveals Ancient Constraints Affecting Disease Marker Discovery

Genome-wide disease association studies contrast genetic variation between disease cohorts and healthy populations to discover single nucleotide polymorphisms (SNPs) and other genetic markers revealing underlying genetic architectures of human diseases. Despite scores of efforts over the past decade...

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Bibliografiske detaljer
Main Authors: Dudley, Joel T., Chen, Rong, Sanderford, Maxwell, Butte, Atul J., Kumar, Sudhir
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Letters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424407/
https://ncbi.nlm.nih.gov/pubmed/22389448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss079
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