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A T cell receptor affinity threshold regulates memory CD4 T cell differentiation following vaccination
Diverse Ag-specific memory TCR repertoires are essential for protection against pathogens. Subunit vaccines that combine peptide or protein Ags with TLR agonists are very potent at inducing T cell immune responses but their capacity to elicit stable and diverse memory CD4 T cell repertoires has not...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424363/ https://ncbi.nlm.nih.gov/pubmed/22844120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200453 |
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