Origin and differentiation of human memory CD8 T cells after vaccination

The differentiation of human memory CD8 T cells is not well understood. Here we address this issue using the live yellow fever virus (YFV) vaccine, which induces long-term immunity in humans. We used in vivo deuterium labelling to mark CD8 T cells that proliferated in response to the virus and then...

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Vydáno v:Nature
Hlavní autoři: Akondy, Rama S., Fitch, Mark, Edupuganti, Srilatha, Yang, Shu, Kissick, Haydn T., Li, Kelvin W., Youngblood, Ben A., Abdelsamed, Hossam A., McGuire, Donald J., Cohen, Kristen W., Alexe, Gabriela, Nagar, Shashi, McCausland, Megan M., Gupta, Satish, Tata, Pramila, Haining, W. Nicholas, McElrath, M. Juliana, Zhang, David, Hu, Bin, Greenleaf, William J., Goronzy, Jorg J., Mulligan, Mark J., Hellerstein, Marc, Ahmed, Rafi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037316/
https://ncbi.nlm.nih.gov/pubmed/29236685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24633
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