Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage

Lymphatic vessels transport interstitial fluid, soluble antigen, and immune cells from peripheral tissues to lymph nodes (LNs), yet the contribution of peripheral lymphatic drainage to adaptive immunity remains poorly understood. We examined immune responses to dermal vaccination and contact hyperse...

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Bibliographic Details
Main Authors: Thomas, Susan N., Rutkowski, Joseph M., Pasquier, Miriella, Kuan, Emma L., Alitalo, Kari, Randolph, Gwendalyn J., Swartz, Melody A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424306/
https://ncbi.nlm.nih.gov/pubmed/22844119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103545
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