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Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung

Chitin exposure in the lung induces eosinophilia and alternative activation of macrophages, and is correlated with allergic airway disease. However, the mechanism underlying chitin-induced polarization of macrophages is poorly understood. Here, we show that chitin induces alternative activation of m...

詳細記述

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書誌詳細
主要な著者: Roy, René M., Wüthrich, Marcel, Klein, Bruce S.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424300/
https://ncbi.nlm.nih.gov/pubmed/22851704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200689
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