Complement Component 3C3 and C3a Receptor Are Required in Chitin-Dependent Allergic Sensitization to Aspergillus fumigatus but Dispensable in Chitin-Induced Innate Allergic Inflammation

Levels of the anaphylatoxin C3a are increased in patients with asthma compared with those in nonasthmatics and increase further still during asthma exacerbations. However, the role of C3a during sensitization to allergen is poorly understood. Sensitization to fungal allergens, such as Aspergillus fu...

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Detalhes bibliográficos
Main Authors: Roy, René M., Paes, Hugo C., Nanjappa, Som G., Sorkness, Ron, Gasper, David, Sterkel, Alana, Wüthrich, Marcel, Klein, Bruce S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622928/
https://ncbi.nlm.nih.gov/pubmed/23549917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00162-13
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