Runx2 Haploinsufficiency Ameliorates the Development of Ossification of the Posterior Longitudinal Ligament

Ossification of the Posterior Longitudinal Ligament (OPLL) is a disease that is characterized by the ectopic calcification of the ligament; however, the pathogenesis of OPLL remains to be investigated. We attempted to identify the in vivo role of Runx2, a master regulator of osteoblast differentiati...

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Detalhes bibliográficos
Main Authors: Iwasaki, Makiko, Piao, Jinying, Kimura, Ayako, Sato, Shingo, Inose, Hiroyuki, Ochi, Hiroki, Asou, Yoshinori, Shinomiya, Kenichi, Okawa, Atsushi, Takeda, Shu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424156/
https://ncbi.nlm.nih.gov/pubmed/22927960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043372
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