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Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancement
BACKGROUND: Dengue viruses (DENV) are the most important arboviruses of humans and cause significant disease. Infection with DENV elicits antibody responses to the envelope glycoprotein, predominantly against immunodominant, cross-reactive, weakly-neutralizing epitopes. These weakly-neutralizing ant...
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Hoofdauteurs: | , , |
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Formaat: | Artigo |
Taal: | Inglês |
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BioMed Central
2012
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424142/ https://ncbi.nlm.nih.gov/pubmed/22709350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-115 |
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