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Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancement
BACKGROUND: Dengue viruses (DENV) are the most important arboviruses of humans and cause significant disease. Infection with DENV elicits antibody responses to the envelope glycoprotein, predominantly against immunodominant, cross-reactive, weakly-neutralizing epitopes. These weakly-neutralizing ant...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424142/ https://ncbi.nlm.nih.gov/pubmed/22709350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-115 |
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