Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11

Recent genome-wide association studies of pediatric IBD have implicated the 17q12 loci, which contains the eosinophil specific chemokine gene CCL11, with early-onset IBD susceptibility. In the present study, we employed a murine model of experimental colitis to define the molecular pathways that reg...

Full description

Saved in:
Bibliographic Details
Main Authors: Waddell, Amanda, Ahrens, Richard, Steinbrecher, Kris, Donovan, Burke, Rothenberg, Marc E., Munitz, Ariel, Hogan, Simon P.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423906/
https://ncbi.nlm.nih.gov/pubmed/21498668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003844
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items