Ly6G ligation blocks recruitment of neutrophils via a β2-integrin–dependent mechanism

Ly6G is a glycosylphosphatidylinositol (GPI)–anchored protein of unknown function that is commonly targeted to induce experimental neutrophil depletion in mice. In the present study, we found that doses of anti-Ly6G Abs too low to produce sustained neutropenia remained capable of inhibiting experime...

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Главные авторы: Wang, Jun-Xia, Bair, Angela M., King, Sandra L., Shnayder, Ruslan, Huang, Ya-Fang, Shieh, Chi-Chang, Soberman, Roy J., Fuhlbrigge, Robert C., Nigrovic, Peter A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2012
Предметы:
Phagocytes, Granulocytes, and Myelopoiesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423786/
https://ncbi.nlm.nih.gov/pubmed/22661700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-404046
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