Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer

Cancer immune evasion is an emerging hallmark of disease progression. We have demonstrated previously that impaired actin polymerization at the T-cell immunologic synapse is a global immune dysfunction in chronic lymphocytic leukemia (CLL). Direct contact with tumor cells induces defective actin pol...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ramsay, Alan G., Clear, Andrew J., Fatah, Rewas, Gribben, John G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423779/
https://ncbi.nlm.nih.gov/pubmed/22547582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-411678
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares