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Hantavirus Regulation of Type I Interferon Responses

Hantaviruses primarily infect human endothelial cells (ECs) and cause two highly lethal human diseases. Early addition of Type I interferon (IFN) to ECs blocks hantavirus replication and thus for hantaviruses to be pathogenic they need to prevent early interferon induction. PHV replication is blocke...

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Autors principals: Matthys, Valery, Mackow, Erich R.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423653/
https://ncbi.nlm.nih.gov/pubmed/22924041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/524024
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