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Hantavirus Interferon Regulation and Virulence Determinants

Hantaviruses predominantly replicate in primary human endothelial cells and cause 2 diseases characterized by altered barrier functions of vascular endothelium. Most hantaviruses restrict the early induction of interferon-β (IFNβ) and interferon stimulated genes (ISGs) within human endothelial cells...

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Autors principals: Mackow, Erich R., Dalrymple, Nadine A., Cimica, Velasco, Matthys, Valery, Gorbunova, Elena, Gavrilovskaya, Irina
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058395/
https://ncbi.nlm.nih.gov/pubmed/24412542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.12.041
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