The Potassium Channel, Kir3.4 Participates in Angiotensin II-Stimulated Aldosterone Production by a Human Adrenocortical Cell Line

Angiotensin II (A-II) regulation of aldosterone secretion is initiated by inducing cell membrane depolarization, thereby increasing intracellular calcium and activating the calcium calmodulin/calmodulin kinase cascade. Mutations in the selectivity filter of the KCNJ5 gene coding for inward rectifyin...

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Hlavní autoři: Oki, Kenji, Plonczynski, Maria W., Lam, Milay Luis, Gomez-Sanchez, Elise P., Gomez-Sanchez, Celso E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Glucocorticoids-CRH-ACTH-Adrenal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423613/
https://ncbi.nlm.nih.gov/pubmed/22798349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1241
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