Angiotensin II and III Metabolism and Effects on Steroid Production in the HAC15 Human Adrenocortical Cell Line

Aldosterone is synthesized in the zona glomerulosa of the adrenal cortex under primary regulation by the renin-angiotensin system. Angiotensin II (A-II) acts through the angiotensin types 1 and 2 receptors (AT1R and AT2R). A-II is metabolized in different tissues by various enzymes to generate two h...

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Detalhes bibliográficos
Main Authors: Oki, Kenji, Kopf, Phillip G., Campbell, William B., Luis Lam, Milay, Yamazaki, Takeshi, Gomez-Sanchez, Celso E., Gomez-Sanchez, Elise P.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Glucocorticoids-CRH-ACTH-Adrenal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529373/
https://ncbi.nlm.nih.gov/pubmed/23221601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1557
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