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Near-infrared Fluorescent Divalent RGD Ligand for Integrin α(v)β(3)-targeted Optical Imaging
A new near-infrared fluorescent compound containing two cyclic RGD motifs, cypate-[c(RGDfK)](2) (1), was synthesized based on a carbocyanine fluorophore bearing two carboxylic acid groups (cypate) for integrin α(v)β(3)-targeting. Compared with its monovalent counterpart cypate-c(RGDfK) (2), 1 exhibi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423536/ https://ncbi.nlm.nih.gov/pubmed/22871580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.07.044 |
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