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Multimodal Imaging of Integrin Receptor-Positive Tumors by Bioluminescence, Fluorescence, Gamma Scintigraphy and SPECT Methods Using a Cyclic RGD Peptide Labeled with a Near Infrared Fluorescent Dye and a Radionuclide
Integrins, particularly the α(v)β(3) heterodimers, play important roles in tumor-induced angiogenesis and invasiveness. To image the expression pattern of the α(v)β(3) integrin in tumors through a multimodality imaging paradigm, we prepared a cyclic RGDyK peptide analog (LS308) bearing a tetraazamac...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975541/ https://ncbi.nlm.nih.gov/pubmed/19397855 |
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