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How the protease thrombin talks to cells

How does a protease act like a hormone to regulate cellular functions? The coagulation protease thrombin (EC 3.4.21.5) activates platelets and regulates the behavior of other cells by means of G protein-coupled protease-activated receptors (PARs). PAR1 is activated when thrombin binds to and cleaves...

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Autor principal: Coughlin, Shaun R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC34235/
https://ncbi.nlm.nih.gov/pubmed/10500117
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