Combined Species Identification, Genotyping, and Drug Resistance Detection of Mycobacterium tuberculosis Cultures by MLPA on a Bead-Based Array

The population structure of Mycobacterium tuberculosis is typically clonal therefore genotypic lineages can be unequivocally identified by characteristic markers such as mutations or genomic deletions. In addition, drug resistance is mainly mediated by mutations. These issues make multiplexed detect...

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Autors principals: Bergval, Indra, Sengstake, Sarah, Brankova, Nadia, Levterova, Viktoria, Abadía, Edgar, Tadumaze, Nino, Bablishvili, Nino, Akhalaia, Maka, Tuin, Kiki, Schuitema, Anja, Panaiotov, Stefan, Bachiyska, Elizabeta, Kantardjiev, Todor, de Zwaan, Rina, Schürch, Anita, van Soolingen, Dick, van ‘t Hoog, Anja, Cobelens, Frank, Aspindzelashvili, Rusudan, Sola, Christophe, Klatser, Paul, Anthony, Richard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423362/
https://ncbi.nlm.nih.gov/pubmed/22916230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043240
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