Pre-Existing Isoniazid Resistance, but Not the Genotype of Mycobacterium Tuberculosis Drives Rifampicin Resistance Codon Preference in Vitro

Both the probability of a mutation occurring and the ability of the mutant to persist will influence the distribution of mutants that arise in a population. We studied the interaction of these factors for the in vitro selection of rifampicin (RIF)-resistant mutants of Mycobacterium tuberculosis. We...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bergval, Indra, Kwok, Brian, Schuitema, Anja, Kremer, Kristin, van Soolingen, Dick, Klatser, Paul, Anthony, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250395/
https://ncbi.nlm.nih.gov/pubmed/22235262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029108
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky