Resistant mutants of Mycobacterium tuberculosis selected in vitro do not reflect the in vivo mechanism of isoniazid resistance

OBJECTIVES: The high prevalence of isoniazid-resistant Mycobacterium tuberculosis is often explained by a high mutation rate for this trait, although detailed information to support this theory is absent. We studied the development of isoniazid resistance in vitro, making use of a laboratory strain...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Bergval, Indra L., Schuitema, Anja R. J., Klatser, Paul R., Anthony, Richard M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724981/
https://ncbi.nlm.nih.gov/pubmed/19578178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp237
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki