Optimizing multiplex SNP-based data analysis for genotyping of Mycobacterium tuberculosis isolates

BACKGROUND: Multiplex ligation-dependent probe amplification (MLPA) is a powerful tool to identify genomic polymorphisms. We have previously developed a single nucleotide polymorphism (SNP) and large sequence polymorphisms (LSP)-based MLPA assay using a read out on a liquid bead array to screen for...

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Autori principali: Sengstake, Sarah, Bablishvili, Nino, Schuitema, Anja, Bzekalava, Nino, Abadia, Edgar, de Beer, Jessica, Tadumadze, Nona, Akhalaia, Maka, Tuin, Kiki, Tukvadze, Nestani, Aspindzelashvili, Rusudan, Bachiyska, Elizabeta, Panaiotov, Stefan, Sola, Christophe, van Soolingen, Dick, Klatser, Paul, Anthony, Richard, Bergval, Indra
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Methodology Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117977/
https://ncbi.nlm.nih.gov/pubmed/25001491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-572
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