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IBD is a Disorder of Defective Autophagy and Innate Immunity: Endoplasmic Reticulum Stress and Inflammation
Endoplasmic reticulum (ER) stress due to the presence of misfolded or unfolded proteins in the ER invokes a fundamental biological response, termed the Unfolded Protein Response (UPR). The UPR is orchestrated by three main proximal effectors, of which the IRE1/XBP1 pathway represents the evolutionar...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423328/ https://ncbi.nlm.nih.gov/pubmed/22796794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000338121 |
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