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IBD is a Disorder of Defective Autophagy and Innate Immunity: Endoplasmic Reticulum Stress and Inflammation

Endoplasmic reticulum (ER) stress due to the presence of misfolded or unfolded proteins in the ER invokes a fundamental biological response, termed the Unfolded Protein Response (UPR). The UPR is orchestrated by three main proximal effectors, of which the IRE1/XBP1 pathway represents the evolutionar...

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Autors principals: Adolph, Timon-Eric, Niederreiter, Lukas, Blumberg, Richard S, Kaser, Arthur
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423328/
https://ncbi.nlm.nih.gov/pubmed/22796794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000338121
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