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Crohn’s disease: NOD2, autophagy and ER stress converge
Polymorphisms in NOD2, encoding an intracellular pattern recognition receptor, contribute the largest fraction of genetic risk for Crohn’s disease among the >40 risk loci identified so far. Autophagy plays a prominent role in the innate immune response towards intracellular bacteria. The discover...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897479/ https://ncbi.nlm.nih.gov/pubmed/21252204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2009.206466 |
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