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Protein Disulfide Isomerase-associated 6 is an ATF6-inducible ER Stress Response Protein that Protects Cardiac Myocytes from Ischemia/Reperfusion-mediated Cell Death

Proper folding of secreted and transmembrane proteins made in the rough endoplasmic reticulum (ER) requires oxygen for disulfide bond formation. Accordingly, ischemia can impair ER protein folding and initiate the ER stress response, which we previously showed is activated in the ischemic heart and...

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Detalhes bibliográficos
Main Authors: Vekich, John A., Belmont, Peter J., Thuerauf, Donna J., Glembotski, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423192/
https://ncbi.nlm.nih.gov/pubmed/22609432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.05.005
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