ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart

RATIONALE: ER stress causes accumulation of misfolded proteins in the ER, activating the transcription factor, ATF6, which induces ER stress response genes. Myocardial ischemia induces the ER stress response; however, neither the function of this response nor whether it is mediated by ATF6 is known....

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Publié dans:Circ Res
Auteurs principaux: Jin, Jung-Kang, Blackwood, Erik A., Azizi, Khalid, Thuerauf, Donna J., Fahem, Asal G., Hofmann, Christoph, Kaufman, Randal J., Doroudgar, Shirin, Glembotski, Christopher C.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336510/
https://ncbi.nlm.nih.gov/pubmed/27932512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.310266
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