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Protein Disulfide Isomerase-associated 6 is an ATF6-inducible ER Stress Response Protein that Protects Cardiac Myocytes from Ischemia/Reperfusion-mediated Cell Death

Proper folding of secreted and transmembrane proteins made in the rough endoplasmic reticulum (ER) requires oxygen for disulfide bond formation. Accordingly, ischemia can impair ER protein folding and initiate the ER stress response, which we previously showed is activated in the ischemic heart and...

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Détails bibliographiques
Auteurs principaux: Vekich, John A., Belmont, Peter J., Thuerauf, Donna J., Glembotski, Christopher C.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423192/
https://ncbi.nlm.nih.gov/pubmed/22609432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.05.005
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