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Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load

Intracellular calcium (Ca) alternans in cardiac myocytes have been shown in many experimental studies, and the mechanisms remain incompletely understood. We recently developed a “3R theory” that links Ca sparks to whole cell Ca alternans through three critical properties: randomness of Ca sparks; re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nivala, Michael, Qu, Zhilin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423167/
https://ncbi.nlm.nih.gov/pubmed/22661509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00302.2012
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